Relationship between DNA damage and sperm head birefringence
نویسندگان
چکیده
منابع مشابه
Relationship between reactive oxygen species production in human semen and sperm DNA damage assessed by Sperm Chromatin Structure Assay.
AIM The aim of this prospective study was to find possible relationship between ROS production measured by chemiluminescence and flow cytometry in human semen and sperm DNA damage estimated by Sperm Chromatin Structure Assay. METHODS Study included 39 men from infertile couples and 23 fertile volunteers who served as a control group. Aliquot of neat semen was used for ROS detection by chemilu...
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DNA fragmentation in human sperm has been related to endogenous and exogenous factors. Exogenous factors can also affect leukocyte DNA integrity. This study evaluated the relation between sperm DNA damage and leukocyte DNA integrity, as a predictor of exogenous factors. DNA damage in the sperm and leukocytes of 41 individuals undergoing ICSI were measured by Comet assay. In addition, sperm chro...
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BACKGROUND In humans, sperm DNA fragmentation rates have been correlated with sperm viability rates. Reduced sperm viability is associated with high sperm DNA fragmentation, while conversely high sperm viability is associated with low rates of sperm DNA fragmentation. Both elevated DNA fragmentation rates and poor viability are correlated with impaired male fertility, with a DNA fragmentation r...
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Introduction: tegrity is the most important component for transferring genetic information Sperm DNA fragmentation is considered a component of male infertility. Its assessment comprises conventional semen analysis of which emphasis is placed on its evaluation in fertility clinics. In this study, we investigate the relationship between sperm parameters of motility, morphology, concentratio...
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This study explored the correlation between sperm ultrastructure in infertile patients with abnormal sperm morphology and DNA damage. Three unusual sperm morphologies were selected for the experimental group namely case 1 (95% headless sperm), case 2 (98% headless sperm), and case 3 (100% headless sperm), and the control group consisted of 2 subjects (20 and 15% headless sperm). For case 1, the...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2011
ISSN: 1472-6483
DOI: 10.1016/j.rbmo.2011.03.017